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nature medicine semaglutide A trial emulation in Nature Medicine shows that treatment with semaglutide and tirzepatide showed similar levels of benefit on cardiovascular outcomes in people at elevated cardiovascular risk with obesity and diabetes. Link

Marsoni M251S
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4.8 ★★★★★
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Morgan prickett
San Leandro, US
★★★★★ 5
I Import These to Mexico That's How Good They Are
I have purchased this bone at least 10 times and will keep buying it indefinitely. I have 8 rescue dogs, all extreme chewers , we're talking dogs that destroy absolutely everything. This is the only bone I've found that holds their interest and keeps them coming back for more. I've tried every type of bone on the market. This one wins! My dogs range from 5 lbs to 100 lbs and every single one of them is equally obsessed. I now order 5 at a time because I know they'll all be used. The price point is excellent for what you get, and after constant use across 8 dogs, I haven't noticed any negative effects on their health or teeth. I love these so much that I actually import them to Mexico, that should tell you everything. Every time someone visits and sees how occupied and happy my dogs are, they immediately ask where they can get them too. Benebone, you have a customer for life!!!!!!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 28, 2026
K
Verified Purchase
Kym Brunner
New York, US
★★★★★ 5
Aggressive Chewers' Delight!
Super strong and apparently flavorful, my aggressive chewing puppy loves this! Goes at it for ten minutes at a time, several times per day - woohoo!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 3, 2026
S
Verified Purchase
Sarah Margaret Goodman
Alexandria, US
★★★★★ 5
Dogs love them and they are very safe for them to chew!
These bones are indispensable if you have a chewing and destructive puppy! (Or any dog, really) ours love them and never get tired of chewing - so far we have had them for a month and no one is tired of them or more importantly has managed to eat any of them. They are a great buy and keep dogs really occupied when they may get bored and feel like causing trouble or chewing something!
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Reviewed in the United States on May 1, 2026
C
Verified Purchase
Cindy Knox
Carnegie, US
★★★★★ 5
Great toy
My dog absolutely loves this toy! Pretty durable, good for moderate to light aggression.
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Reviewed in the United States on July 29, 2025
M
Verified Purchase
Moxie1010
Houston, US
★★★★★ 5
80lb Dog Goes Wild Over This Pulpo
My dog goes wild over this toy. The key difference between this and other octopus chew and rip toys is that this has a head horn, crinkle legs, and a squeaker in every limb. It makes it so much fun to play with him. After he destroys the sounds, he parades it around for his victory show.
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Reviewed in the United States on May 30, 2024

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