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glp 1 multiple sclerosis Phase 2 pegsebrenatide trial begins dosing in progressive MS

Marsoni M251S
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As GLP 1 weight loss drugs become more common, questions around access, affordability and side effects are growing. Dr. Anne Peters explores the latest changes, including new oral options and insurance coverage challenges on Glucagon like peptide 1 receptor agonists in arthritis: current insights and future directions Nature Reviews Rheumatology Have you or someone you know experienced acute pancreatitis when taking GLP 1 medicine for weight loss or T2 diabetes? The success of GLP 1 medicines, such as Ozempic or Wegovy, in supporting Pediatric trials aim to expand GLP 1 weight loss drugs to younger children GLP TRIM A Natural GLP 1 Alternative Medi Weightloss Myth vs Fact: Peptides + GLP 1s let's clear the confusion. There's a lot of buzz around weight loss injections and peptides, but they're not the same and neither is
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4.8 ★★★★★
Based on 213 reviews
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Verified Purchase
Meagan patterson
Phoenix, US
★★★★★ 3
Not for puppies that like to chew
Style: Monkey
Tore really quickly
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 12, 2025
C
Verified Purchase
CMad
Alexandria, US
★★★★★ 1
DO NOT BUY THIS TOY FOR A DOG
Style: Hedgehog
I purchased this toy for my Mothers 11 pound female 10 years old rescue dog. Under 1 hour the dog chewed off all the feet, the nose, and then started to pull off the fur. We took it away. Dangerous!!! The description list for Aggressive Chewers it is not!!!
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Reviewed in the United States on December 17, 2024
E
Elle
Lake Worth, US
★★★★★ 5
Very High-Quality Hedgehog Dog Toy That’s Bigger Than Expected
Style: Hedgehog
I am SO happy with this -- it's a nice surprise to get a dog toy that is this nice quality-wise! This plush toy is well-made and much larger than I thought it would be. The stitching is solid, and the material holds up to rough chewing. My dog’s been playing with it daily and it still looks good. The squeaker’s not too loud, and the soft texture makes it perfect for tugging or tossing.
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Reviewed in the United States on May 1, 2025
V
Vineyard Cow
Phoenix, US
★★★★★ 4
Very Soft Toy
Style: Hedgehog
This stuffed hedgehog is very soft and has a really nice squeaker in it. I can already tell that it will absolutely not hold up to an aggressive chewer, but it will be fun for a day or two for my pup. It would probably be way better as a giant toy for a tiny dog, but it was so cute that I couldn't resist for my husky mix.
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Reviewed in the United States on April 21, 2025
W
Verified Purchase
Wiseoldman
West Palm Beach, US
★★★★★ 5
Brindle Boxer and yellow lab, 2 different approaches
Style: Talking Babble, Size: Medium
Our Brindle Boxer absolutely loves this toy! We got one of the small babble balls from a friend and "Baron" took right to it. Very funny watching him, once he realized that when he bumped or otherwise jostled it, it would talk! After about an hour of him tossing and "nosing" it around (not bad on carpet but on our hardwood floors, it can get a little grating), he started chewing on it. We're like, "OK, here we go, how long is this thing going to last now?". To our surprise, it's holding up pretty well. He's a chewer that can really munch down when he gets into a "groove" and it is taking a beating although it is not indestructible so keep an eye on it. There are 2 screws that hold the door in, which is crafted very well but be sure they are always in there tight. To avoid any issues, once we replaced the batteries the 1st time, we took out the screws and glued the door in and left the screws out. By the time the batteries are dead this time, the ball will be ready to throw out for sure. Not bad for longevity IMHO. Our dogs can chew a Kong ball up in a couple days once they get a crack in it. if there's a weak point on a dog toy, our dog will find it!....:-) Our other dog is Dusty, our yellow lab. Sweet loving dog with that "lab" mentality", all love and slobber :-) He looks at the Babble ball with mild amusement and walks on past it. Every once in awhile, he'll pick it up but that's usually only a ploy he uses when we're petting the "other one" (A name, we're sure Dusty uses when he refers to Baron). I imagine he would actually like this toy more, had Baron not taken it and cuddled it like his own new born baby the second it hit the floor and commandeered the 2nd one just as fast!! :-) The Small size one (A little larger than a golf ball) has ridges on it and takes a beating. Once it started looking haggard and the batteries started to die, we would put it up and only bring it out for short periods to prolong the life of it until we could find where these were sold. Baron had become "addicted to the darn thing! :-) He would whine and stare at it on the shelf for what seemed like hours until one of us would get it down and give it to him. Since the small one seemed just "bit small" for our Boxer for our tastes and surely too small for our lab, we decided to get the next size up. The Medium one has a smooth surface which also holds up very well although, that once "smooth surface", will start to resemble a Tennis ball after a while but it takes a licking and keeps on ticking! The "Talking" is amusing for us for about the 1st hour but it is a little loud with fresh batteries and can be annoying when watching TV or talking on the phone. After about a week though, the batteries start to drain some and the volume goes down a bit. Baron will only pick it up a few times a day from there on out so when he gets in the mood, he'll toss it around for about 15 minutes then leave it alone for a while. I can work with that. :-) All in all, We are impressed with the quality AND the "FUN FACTOR" for both us, and our Puppies! We're Babble ball fans for life! (Can we get a discount, if we buy them by the case? :-)
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Reviewed in the United States on March 5, 2011

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