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Friday, May 29
The power of three: Retatrutide's role in modern obesity and diabetes therapy ScienceDirect Dual Incretin Revolution: Tirzepatide's Mechanism and Clinical Impact in Obesity & Diabetes Comment Curious for the deep dive A new 2026 study suggests we might have been totally wrong about GLP 1s and muscle mass loss. These data suggest GLP 1 receptor agonists may not Biased agonism of GLP 1R and GIPR enhances glucose lowering and weight loss, with dual GLP 1R GIPR biased agonism yielding greater efficacy: Cell Reports Medicine What is GLP 1? Benefits, Uses and Side Effects Swanson Swanson Vitamins List of GLP 1 Receptor Agonists for Diabetes & Weight Loss
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Snazzy Shoes
Size: 11.5 Wide, Color: Truffle/Ivory
Look nice, comfortable, easy to slip on
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Reviewed in the United States on April 13, 2026
★★★★★ 5
Nice comfortable shoes
Size: 8.5, Color: Iron Nubuck/Iron
Looks good. Comfortable shoe.
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Reviewed in the United States on May 29, 2026
★★★★★ 5
Great product, great delivery!
Size: 10.5 Wide, Color: Navy Blazer/Ivory
Great shoe- saw them in Nordstrom and was pleased to see I could get them quickly on Amazon. Arrived quickly and were packaged well!
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Reviewed in the United States on May 20, 2026
★★★★★ 5
Fit and comfort
Size: 12, Color: Ch British Tan/Ivory
These have to rate as equal to any shoes I've ever owned. I know everyone's foot is shaped differently but when I slipped my feet into these I was immediately sure I had made the correct choice. Sizing is true.
You note, I'm sure, that these are slip-on shoes. My experience with slip-ons has been mixed as sometimes the heel tends to slip due to the maker leaving room for the slip-on function to take place. When I got these I discovered that the opening for my feet was so tight I needed to shoe-horn them in and it wasn't particularly easy. The heel counter was "high and tight" but once I got my feet in the shoes it was heaven. Then, after a couple of days wearing them I can now slip my feet into these slip-ons with ease and the shoes grip my feet like a lace-up shoe can do.
I have one other pair of Cole Haans in the same size 12. They are also a wonderful fit for me.
I highly recommend.
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Reviewed in the United States on April 8, 2025
★★★★★ 4
Great shoes true to size
Size: 11, Color: Ivory/Microchip/Ivory, Size: 11, Color: Ivory/Microchip/Ivory
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3 month update: They get wrinkles pretty fast in just a few weeks due to the material, it’s not noticeable to others at all, but it’s worth keeping this in mind when buying this particular model.
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